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Altogether, our facts give evidence with the possible of combining CX-5461 and PARPi for improving upon the treatment method of HR-deficient HGSOC. We reveal that CX-5461 enhances the artificial lethal interaction of PARPi with HRD and Evidently present that CX-5461 has another system of motion to PARPi. Importantly, we characterised BRCA-mutated a
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